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Portfolio Holdings

American Funds Insurance Series - Growth-Income Fund

As of September 30, 2017 (updated quarterly, upon availability)

Fixed-Income Securities* Shares or Principal Amount Market Value
APPLE INC 4(2) CP 10/18/2017 70,500,000 70,459,181
APPLE INC 4(2) CP 10/3/2017 41,031,000 41,026,076
APPLE INC 4(2) CP 12/11/2017 55,000,000 54,871,630
BANK OF NY MELLON CP 11/20/2017 50,000,000 49,912,600
CIESCO LLC 4(2) CP 11/15/2017 45,000,000 44,925,255
CISCO SYSTEMS INC 4(2) CP 12/12/2017 40,000,000 39,905,200
CISCO SYSTEMS INC 4(2) CP 12/20/2017 84,000,000 83,776,308
COCA-COLA CO 4(2) CP 11/9/2017 25,000,000 24,968,350
DISNEY WALT CO 4(2) CP 10/12/2017 25,000,000 24,989,850
ESTEE LAUDER 4(2) CP 11/10/2017 25,000,000 24,964,925
EXXON CORP CP 11/1/2017 50,000,000 49,950,000
FED HM LN BK BD 10/3/2017 60,200,000 60,198,194
FED HM LN BK BD 10/4/2017 43,500,000 43,497,825
FED HM LN BK BD 10/6/2017 50,000,000 49,994,500
FED HM LN BK BD 11/14/2017 42,400,000 42,349,968
FED HM LN BK BD 11/22/2017 50,000,000 49,928,500
FED HM LN BK BD 11/28/2017 25,000,000 24,959,250
FED HM LN BK BD 11/3/2017 90,000,000 89,922,600
FED HM LN BK BD 11/8/2017 93,300,000 93,204,834
FED HM LN BK BD 12/29/2017 50,000,000 49,869,000
FED HM LN BK DISC NT 12-13-17 50,000,000 49,895,000
FED HM LN MTG CORP DISC NT 3/1/2018 50,000,000 49,757,000
FED HM LN MTG CORP DISC NT 3/2/2018 50,000,000 49,755,500
GENERAL ELECTRIC CP 10/2/2017 26,900,000 26,897,579
JOHN DEERE CAPITAL CORP 4(2) CP 10/11/2017 23,200,000 23,191,323
JOHNSON & JOHNSON 4(2) CP 10/13/2017 15,300,000 15,293,498
JOHNSON & JOHNSON 4(2) CP 10/24/2017 20,700,000 20,684,165
JOHNSON & JOHNSON 4(2) CP 10/5/2017 50,000,000 49,990,950
MICROSOFT CORP 4(2) CP 10/10/2017 21,500,000 21,492,841
MICROSOFT CORP 4(2) CP 10/3/2017 40,800,000 40,795,104
PACCAR FINL CORP CP 11/3/2017 19,000,000 18,979,311
PFIZER INC 4(2) CP 10/10/2017 42,300,000 42,285,914
PFIZER INC 4(2) CP 10/17/2017 75,000,000 74,958,900
PFIZER INC 4(2) CP 12/18/2017 75,000,000 74,805,825
PROCTER & GAMBLE 4(2) CP 1/18/2018 25,000,000 24,906,500
PROCTER & GAMBLE 4(2) CP 1/3/2018 74,500,000 74,263,016
PROCTER & GAMBLE 4(2) CP 11/2/2017 45,000,000 44,952,930
QUALCOMM INC 4(2) CP 11/7/2017 19,100,000 19,075,762
U S TREASURY BILL 1/11/2018 40,800,000 40,685,352
U.S. Treasury 1.625% 2026 59,900,000 56,774,418
UNITED PARCEL SVC 4(2) CP 11/1/2017 25,000,000 24,973,950
VeriSign, Inc., convertible notes, 3.25% 2037 18,020,000 56,154,825
WAL-MART STORES 4(2) CP 10/10/2017 60,000,000 59,980,020
WAL-MART STORES 4(2) CP 10/16/2017 75,100,000 75,061,098
Weatherford International PLC 5.875% 2021 43,359,407 47,451,451
Equity Securities* Shares or Principal Amount Market Value Percent of Net Assets
AES Corp. 1,631,000 17,973,620 0.06
ASML Holding NV (New York registered) 663,700 113,625,440 0.39
AT&T Inc. 597,500 23,404,075 0.08
AbbVie Inc. 7,549,600 670,857,456 2.28
Abbott Laboratories 2,148,800 114,659,968 0.39
Accenture PLC, Class A 1,654,500 223,473,315 0.76
Advance Auto Parts, Inc. 513,300 50,919,360 0.17
Agios Pharmaceuticals, Inc. 639,500 42,686,625 0.15
Air Lease Corp., Class A 1,415,000 60,307,300 0.20
Airbus SE, non-registered shares 1,674,764 159,408,317 0.54
Albemarle Corp. 199,000 27,125,690 0.09
Alexion Pharmaceuticals, Inc. 57,000 7,996,530 0.03
Alphabet Inc., Class A 373,700 363,879,164 1.24
Alphabet Inc., Class C 309,284 296,637,377 1.01
Altaba Inc. 1,822,500 120,722,400 0.41
Altria Group, Inc. 1,720,000 109,082,400 0.37
Amazon.com, Inc. 1,061,200 1,020,184,620 3.47
American International Group, Inc. 2,716,489 166,765,260 0.57
American Tower Corp. REIT 515,800 70,499,544 0.24
Ameriprise Financial, Inc. 101,100 15,014,361 0.05
Amgen Inc. 2,858,916 533,044,888 1.81
Aon PLC, Class A 1,214,800 177,482,280 0.60
Apache Corp. 1,100,000 50,380,000 0.17
Apple Inc. 2,196,800 338,570,816 1.15
Aramark 2,655,200 107,827,672 0.37
Arista Networks, Inc. 250,828 47,559,497 0.16
Asahi Kasei Corp. 619,000 7,626,808 0.03
Avon Products, Inc. 19,099,000 44,500,670 0.15
BB&T Corp. 3,486,000 163,632,840 0.56
BP PLC 6,978,185 44,616,130 0.15
BWX Technologies, Inc. 2,248,165 125,942,203 0.43
Baker Hughes, a GE Co., Class A 1,247,600 45,687,112 0.16
Banco Santander, SA 16,095,805 112,376,639 0.38
Bank of Montreal 718,327 54,363,149 0.18
Bank of New York Mellon Corp. 4,599,400 243,860,188 0.83
Boeing Co. 123,600 31,420,356 0.11
British American Tobacco PLC 2,271,100 141,990,953 0.48
Broadcom Ltd. 1,575,390 382,095,091 1.30
C.H. Robinson Worldwide, Inc. 1,363,035 103,726,964 0.35
CBS Corp., Class B 720,000 41,760,000 0.14
CME Group Inc., Class A 502,900 68,233,472 0.23
CSX Corp. 5,777,000 313,460,020 1.07
CVS Health Corp. 1,670,000 135,804,400 0.46
Canadian Natural Resources, Ltd. 3,992,640 133,722,641 0.45
Carlsberg A/S, Class B 1,056,094 115,690,982 0.39
Carnival Corp., units 2,231,700 144,100,869 0.49
Cedar Fair, LP 896,500 57,483,580 0.20
Celanese Corp., Series A 3,364,033 350,767,721 1.19
Centerra Gold Inc. 4,148,009 29,221,398 0.10
Cerner Corp. 1,052,000 75,028,640 0.25
Charter Communications, Inc., Class A 447,669 162,691,868 0.55
Chevron Corp. 1,816,900 213,485,750 0.73
Chubb Ltd. 217,200 30,961,860 0.11
Citigroup Inc. 600,000 43,644,000 0.15
Coach, Inc. 630,000 25,376,400 0.09
Coca-Cola Co. 5,964,900 268,480,149 0.91
Comcast Corp., Class A 6,346,200 244,201,776 0.83
Concho Resources Inc. 574,000 75,607,280 0.26
ConocoPhillips 2,099,410 105,075,471 0.36
Costco Wholesale Corp. 516,000 84,773,640 0.29
Covanta Holding Corp. 2,783,000 41,327,550 0.14
Crown Castle International Corp. REIT 1,428,200 142,791,436 0.49
Daily Mail and General Trust PLC, Class A, non-voting 5,560,000 48,321,110 0.16
Deere & Co. 697,500 87,599,025 0.30
Diageo PLC 1,220,000 40,106,857 0.14
Dollar General Corp. 1,134,400 91,943,120 0.31
DowDuPont Inc. 3,554,100 246,050,343 0.84
EOG Resources, Inc. 2,395,155 231,707,295 0.79
EXOR NV 1,600,000 101,454,296 0.34
East West Bancorp, Inc. 252,000 15,064,560 0.05
Eli Lilly and Co. 659,300 56,396,522 0.19
Enbridge Inc. 1,431,244 59,784,762 0.20
Endo International PLC 240,000 2,055,600 0.01
Exelon Corp. 775,000 29,194,250 0.10
Express Scripts Holding Co. 3,627,500 229,693,300 0.78
Exxon Mobil Corp. 1,088,000 89,194,240 0.30
Ferrari NV 600,000 66,406,301 0.23
First Data Corp., Class A 788,541 14,225,280 0.05
Freeport-McMoRan Inc. 9,055,000 127,132,200 0.43
General Dynamics Corp. 1,122,100 230,681,318 0.78
General Electric Co. 6,075,000 146,893,500 0.50
Gilead Sciences, Inc. 3,972,100 321,819,542 1.09
GoDaddy Inc., Class A 907,200 39,472,272 0.13
Goldman Sachs Group, Inc. 553,980 131,398,516 0.45
HSBC Holdings PLC 11,346,929 111,532,145 0.38
Halliburton Co. 544,800 25,077,144 0.09
Harris Corp. 690,000 90,859,200 0.31
Herbalife Ltd. 756,300 51,299,829 0.17
Hologic, Inc. 2,331,300 85,535,397 0.29
Home Depot, Inc. 1,243,000 203,305,080 0.69
Humana Inc. 938,500 228,646,755 0.78
Huntington Ingalls Industries, Inc. 116,500 26,380,260 0.09
IAC/InterActiveCorp 716,000 84,187,280 0.29
IDEX Corp. 141,900 17,236,593 0.06
Illumina, Inc. 890,300 177,347,760 0.60
Incyte Corp. 1,131,900 132,138,006 0.45
Intel Corp. 9,048,519 344,567,604 1.17
Intercontinental Exchange, Inc. 2,541,065 174,571,166 0.59
International Business Machines Corp. 500,000 72,540,000 0.25
International Flavors & Fragrances Inc. 418,500 59,807,835 0.20
Invesco Ltd. 500,000 17,520,000 0.06
Iron Mountain Inc. REIT 3,811,921 148,283,727 0.50
JPMorgan Chase & Co. 4,639,300 443,099,543 1.51
Johnson & Johnson 890,000 115,708,900 0.39
Juniper Networks, Inc. 107,000 2,977,810 0.01
Kellogg Co. 1,859,000 115,945,830 0.39
KeyCorp 3,270,000 61,541,400 0.21
Kinder Morgan, Inc. 4,108,300 78,797,194 0.27
Kirin Holdings Co., Ltd. 4,229,000 99,570,598 0.34
Kite Pharma, Inc. 198,700 35,728,247 0.12
Kroger Co. 881,400 17,680,884 0.06
L'Oreal SA 470,000 99,863,537 0.34
Las Vegas Sands Corp. 2,129,600 136,635,136 0.46
Leucadia National Corp. 2,340,000 59,085,000 0.20
Lockheed Martin Corp. 109,900 34,100,871 0.12
M&T Bank Corp. 865,900 139,444,536 0.47
MGM Growth Properties LLC REIT, Class A 578,862 17,487,421 0.06
Marks and Spencer Group PLC 4,879,000 23,106,368 0.08
Marriott International, Inc., Class A 572,700 63,145,902 0.21
Marsh & McLennan Companies, Inc. 1,594,100 133,601,521 0.45
Mastercard Inc., Class A 1,100,000 155,320,000 0.53
Medtronic PLC 1,481,673 115,229,709 0.39
Meggitt PLC 3,615,000 25,240,815 0.09
MercadoLibre, Inc. 200,000 51,786,000 0.18
Merck & Co., Inc. 3,714,380 237,831,751 0.81
Microsoft Corp. 8,929,427 665,153,017 2.26
Mondelez International, Inc. 1,774,400 72,147,104 0.25
Monsanto Co. 1,666,485 199,678,233 0.68
Moody's Corp. 447,458 62,290,628 0.21
Morgan Stanley 789,070 38,009,502 0.13
Mosaic Co. 2,522,400 54,458,616 0.19
Motorola Solutions, Inc. 100,000 8,487,000 0.03
NIKE, Inc., Class B 1,663,400 86,247,290 0.29
NetApp, Inc. 1,471,690 64,401,154 0.22
Netflix, Inc. 3,582,277 649,645,934 2.21
Newell Brands Inc. 2,266,300 96,703,021 0.33
Nielsen Holdings PLC 2,211,300 91,658,385 0.31
Noble Energy, Inc. 540,000 15,314,400 0.05
Norfolk Southern Corp. 840,000 111,081,600 0.38
Novartis AG 985,150 84,537,026 0.29
OFG Bancorp, Series C, 8.75% noncumulative convertible preferred 6,000 5,349,000 0.02
ON Semiconductor Corp. 3,270,900 60,413,523 0.21
Occidental Petroleum Corp. 489,000 31,398,690 0.11
Oracle Corp. 3,492,100 168,843,035 0.57
PNC Financial Services Group, Inc. 1,078,276 145,319,257 0.49
PepsiCo, Inc. 998,419 111,253,829 0.38
Pernod Ricard SA 526,446 72,791,767 0.25
Pfizer Inc. 1,995,851 71,251,881 0.24
Philip Morris International Inc. 2,747,430 304,992,204 1.04
Praxair, Inc. 318,300 44,479,242 0.15
Priceline Group Inc. 49,700 90,991,754 0.31
Procter & Gamble Co. 1,887,992 171,769,512 0.58
Progressive Corp. 119,100 5,766,822 0.02
Prudential Financial, Inc. 650,000 69,108,000 0.23
QUALCOMM Inc. 3,519,175 182,434,032 0.62
Qorvo, Inc. 1,144,419 80,887,535 0.27
Quest Diagnostics, Inc. 342,100 32,034,244 0.11
Rio Tinto PLC 1,574,655 73,299,197 0.25
Rockwell Automation 369,900 65,919,879 0.22
Royal Caribbean Cruises Ltd. 771,600 91,465,464 0.31
Royal Dutch Shell PLC, Class A 27,523 829,405 0.00
Royal Dutch Shell PLC, Class A (ADR) 1,150,422 69,692,565 0.24
Royal Dutch Shell PLC, Class B 292,716 9,001,563 0.03
Royal Dutch Shell PLC, Class B (ADR) 680,000 42,527,200 0.14
SAP SE 239,500 26,237,299 0.09
SSE PLC 89,308 1,671,418 0.01
Safran SA 757,903 77,434,156 0.26
Schlumberger Ltd. 2,555,000 178,236,800 0.61
Sempra Energy 1,649,600 188,268,848 0.64
Siemens AG 150,000 21,132,710 0.07
Siemens AG (ADR) 782,000 55,326,500 0.19
Signet Jewelers Ltd. 1,574,500 104,782,975 0.36
Starbucks Corp. 1,353,200 72,680,372 0.25
State Street Corp. 1,544,100 147,523,314 0.50
Stryker Corp. 2,138,141 303,658,785 1.03
Sun Life Financial Inc. 266,200 10,601,064 0.04
Suncor Energy Inc. 953,650 33,422,652 0.11
TOTAL SA 4,493,868 241,695,344 0.82
Takeda Pharmaceutical Co. Ltd. 1,764,000 97,695,301 0.33
Teradata Corp. 1,286,300 43,464,077 0.15
Texas Instruments Inc. 5,181,659 464,483,913 1.58
Textron Inc. 3,365,000 181,306,200 0.62
Thermo Fisher Scientific Inc. 397,500 75,207,000 0.26
Time Warner Inc. 1,546,902 158,480,110 0.54
Toyota Motor Corp. 1,525,000 91,041,602 0.31
TransDigm Group Inc. 344,300 88,020,295 0.30
Trimble Inc. 340,000 13,345,000 0.05
Tullow Oil PLC 9,369,306 23,369,636 0.08
Twenty-First Century Fox, Inc., Class A 6,291,000 165,956,580 0.56
U.S. Bancorp 201,000 10,771,590 0.04
UBS Group AG 1,343,666 22,964,751 0.08
Ultragenyx Pharmaceutical Inc. 695,200 37,026,352 0.13
UniCredit SPA 5,468,000 116,456,578 0.40
Union Pacific Corp. 1,667,633 193,395,399 0.66
United Technologies Corp. 978,300 113,561,064 0.39
UnitedHealth Group Inc. 1,513,596 296,437,777 1.01
Vale SA, ordinary nominative 4,147,848 41,738,445 0.14
Vale SA, ordinary nominative (ADR) 17,367,884 174,894,592 0.59
VeriSign, Inc. 101,400 10,787,946 0.04
Verizon Communications Inc. 10,912,400 540,054,676 1.84
Viacom Inc., Class B 4,600,800 128,086,272 0.44
Visa Inc., Class A 835,100 87,885,924 0.30
Waste Connections, Inc. 662,000 46,313,520 0.16
Waste Management, Inc. 767,700 60,087,879 0.20
Wells Fargo & Co. 3,981,000 219,552,150 0.75
Western Union Co. 400,000 7,680,000 0.03
Weyerhaeuser Co. REIT 4,034,541 137,295,430 0.47
Whitecap Resources Inc. 2,775,000 21,572,831 0.07
Wyndham Worldwide Corp. 272,000 28,671,520 0.10
Wynn Resorts, Ltd. 597,966 89,049,097 0.30
Xilinx, Inc. 1,525,000 108,015,750 0.37
YUM! Brands, Inc. 218,800 16,105,868 0.05
Yum China Holdings, Inc. 218,800 8,745,436 0.03

Investors should carefully consider investment objectives, risks, charges and expenses. This and other important information is contained in the fund prospectuses and summary prospectuses, which can be obtained from a financial professional and should be read carefully before investing.

Investments are not FDIC-insured, nor are they deposits of or guaranteed by a bank or any other entity, so they may lose value.

*
Excludes certain securities in initial period of acquisition.